Does Ritanserin, a Potent Serotonin-S2 Antagonist, Restore Energetic Functions during the Night?
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منابع مشابه
The Serotonin 5-HT2A Receptor Antagonist Ritanserin Induces Apoptosis in Human Colorectal Cancer and Acts in Synergy with Curcumin
Curcumin exhibits both cancer- preventive activity and growth inhibitory effects on several neoplastic cells including human colon cancer. Serotonin and its receptors have also been implicated in tumor development. This study investigated the effect of ritanserin, a selective serotonin 5HT2A receptor antagonist, alone and in combination with curcumin on colorectal cancer cell lines. Result...
متن کاملthe serotonin 5-ht2a receptor antagonist ritanserin induces apoptosis in human colorectal cancer and acts in synergy with curcumin
curcumin exhibits both cancer- preventive activity and growth inhibitory effects on several neoplastic cells including human colon cancer. serotonin and its receptors have also been implicated in tumor development. this study investigated the effect of ritanserin, a selective serotonin 5ht2a receptor antagonist, alone and in combination with curcumin on colorectal cancer cell lines. results sho...
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The potential polyamine antagonist action of N1-dansyl-spermine (a potent NMDA antagonist) was assessed in two in vivo mouse models of polyamine action. Co-administration of N1-dansyl-spermine (2-10 microg, i.c.v.) with spermine (100 microg, i.c.v.) resulted in a dose-dependent antagonism of the spermine-induced CNS excitation (body tremor and fatal tonic convulsions). In addition, the same dos...
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Background: Early diagnosis of appendicitis is important during pregnancy. Unlike omentom, cecum and appendix are not likely to be displaced by the growing uterus, so the concept of position change of the appendix during pregnancy is questionable. Objective: To determine the anatomical location of appendix during pregnancy. Methods: In a prospective study from October 1995 to March 1999, 291 w...
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YM060, (R)-5-[(1-methyl-3-indolyl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole hydrochloride, is a new serotonin (5HT)3-receptor antagonist. We examined the effects of YM060 on chemotherapeutic agent-, apomorphine- and copper sulfate-induced emesis. Intravenous YM060 potently prevented cisplatin (10 mg/kg, i.v.)-induced emesis with ED50 values of 0.06 (0.05-0.07) micrograms/kg, i.v. in ferrets...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1987
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107688708000706